After receiving her MD in Veterinary Medicine (University of Milano, Italy, 1982), Maria Guttinger was a fellow at the Istituto Zooprofilattico Sperimentale della Emilia e della Lombardia, Brescia, Italy and (between 1983 and 1986) she did a Ph.D. in the field of Compared Pathology of Domestic Animals at the University of Milan. Maria Guttinger was a post-doctoral fellow at Hoffmann-La Roche Ltd., Central Research Units, Antigen Presentation Unit, Basel, Switzerland, from 1986 to 1989 and from 1990 to 1991 she was Research Associate at Hoffmann-La Roche Ltd., Central Research Units in the Signal Transduction Unit. In 1992 she was Visiting scientist at the Basel Institute of Immunology (Switzerland). From 1993 to 1995 she was at DIBIT-S. Raffaele Scientific Institute (Milan, Italy) as attending vet, and from 1993 to 2001 she was Group leader at DIBIT-S. Raffaele Scientific Institute. 
Maria Guttinger has directed the Immunology unit at IBCIT-SPR since 2001 and she's attending vet at the University of Rome Tor Vergata (Italy) since 2007.

 

 

Selected publications

 

DeMonte, L., Porcellini, S., Tafi, E., Sheridan, J., Gordon, J., Depreter, M., Blair, N., Panigada, M., Sanvito, F., Merati, B., Albientz, A., Barthlott, T., Ozmen, L., Blackburn, C., Guttinger, M. EVA regulates thymic stromal organization and early thymocyte development. Biochem Biophys Res Commun. May 4;356(2):334-40. (2007).

 

Sampaolesi, M., Blot, S., D’Antona, G., Tonlorenzi, R., Innocenzi, A., Granger, N., Mognol, P., Galvez, B., Perani, P., Mantero, S., Guttinger, M., Pansarasa, O., Rinaldi, C., Cusella De Angelis, M.G., Torrente, Y., Bordignon, C., Bottinelli, R., Cossu, G. Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs. Nature. Nov 30;444(7119):574-9. (2006).

 

Guttinger, M., Tafi, E., Battaglia, M., Coletta, M., Cossu, G.. Allogeneic mesoangioblasts give rise to alpha-sarcoglycan expressing fibers when transplanted into dystrophic mice. Exp Cell Res. Nov 15;312(19):3872-9. (2006).

 

Guttinger, M., Guidi, F., Chinol, M., Reali, E., Veglia, F., Viale, G., Paganelli, G., Corti, A., Siccardi, A.. Adoptive immunotherapy by avidin-driven cytotoxic T lympmphocyte-tumor bridging. Cancer Res., 60: 4211-4215 (2000).

 

Panigada, M., Porcellini, S., Sutti, F., Doneda, L., Pozzoli, O., Consalez, G., Guttinger, M. and Grassi, F.: GKLF in thymus epithelium as a developmentally regulated element of thymocyte-stroma cross-talk. Mech. Develop., 81/1-2:115-125 (1999).

 

Teesalu, T., Grassi, F. and Guttinger, M. Expression pattern of the epithelial V-like antigen (Eva) transcript suggests a possible role in placental morphogenesis. Dev.Gen., 23:317-323 (1998).

 

Guttinger, M., Sutti, F., Panigada, M., Porcellini, S., Merati, B. Mariani, M., Teesalu, T., Consalez, G.G. and Grassi, F. 1998. EVA, a novel member of the immunoglobulin superfamily expressed in embryonic epithelia with a potential role as homotypic adhesion molecule in thymus histogenesis. J. Cell Biol., 141, 1061-1071, (1998).

Resnati M., Guttinger M., Valcamonica S., Sidenius N., Blasi F. and Fazioli F.: Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect . EMBO J., 15 (7), 1572-1582, (1996).

 

Thome, M., Duplay, P., Guttinger M. and Acuto, O.: Syk and ZAP-70 mediate recruitment of p56lck/CD4 to the activated T-cell receptor (TCR)/CD3/z-complex. J.Exp.Med., 181, 1997-2006, (1995).

 

Guttinger M., Sutti, F., Barnier, C., Mackay, C. and Berti, E.: Expression of CD44 standard and variant forms in skin tumors. Loss of CD44 correlates with aggressive potential. Eur.J.Dermatol., 5, 398-406, (1995).